20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid dehydrogenase (20β-HSD).

[1][2] It can be converted by 20β-HSD into progesterone in the uterus.

[3] The effects of 20β-HSD on the uterus, mammary glands, and in maintaining pregnancy have been studied.

[3][4][5] The progestogenic activity of 20β-HSD has also been characterized in women.

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