87 teams contested, beginning on 25 August 2007 and ending at the final on 27 April 2008 at Feijenoord Stadion, in Rotterdam.
Ajax unsuccessfully defended its 2007 title in the round of 16 on 16 January 2008 losing to NAC Breda, 4–2.
Feyenoord successfully pursued its 11th Cup title defeating Roda JC, 2–0, at De Kuip Stadion, Rotterdam.
Türkiyemspor were expelled from the cup tournament as a result of financial problems, their opponents VVSB advanced to the second round automatically.
E Eredivisie; 1 Eerste Divisie; A Amateur teams Feyenoord played in the UEFA Cup.