In the second quarter, the Cardinals took the lead with kicker Neil Rackers getting a 35-yard field goal, while RB Edgerrin James got a 7-yard TD run.

In the fourth quarter, the Cardinals retook the lead with QB Matt Leinart completing a 5-yard TD pass to WR Anquan Boldin.

However, late in the game, the Cards' defense failed to hold off San Francisco's ensuing drive, which ended with WR Arnaz Battle getting a 1-yard TD run.

Hoping to rebound from their tough divisional road loss to the 49ers, the Cardinals played their Week 2 homeopener against another NFC West foe, the Seattle Seahawks.

In the third quarter, the Cardinals' lead was gone with Seattle RB Shaun Alexander getting a 16-yard TD run and kicker Josh Brown getting a 28-yard field goal.

Coming off their divisional home win over the Seahawks, the Cardinals flew to M&T Bank Stadium for an intraconference "bird" battle with the Baltimore Ravens.

In the fourth quarter, Leinart was put back in and the Cardinals didn't miss a beat as rookie WR Steve Breaston returned a punt 73 yards for a touchdown, along with RB Edgerrin James getting a 2-yard TD pass.

Coming off their impressive home win over the Steelers, the Cardinals flew to the Edward Jones Dome for a Week 5 divisional duel with the winless St. Louis Rams.

In the second quarter, the Cardinals trailed again with QB Gus Frerotte completing a 16-yard TD pass to WR Drew Bennett.

However, on the Cards next possession, QB Matt Leinart was sacked by MLB Will Witherspoon, causing his left collarbone to get broken, getting him out for the rest of the game.

Coming off their divisional road win over the Rams, the Cardinals went home for a Week 6 intraconference game against the Carolina Panthers and QB Vinny Testaverde, whom Arizona tried to sign for to back up Warner, yet failed.

In the first quarter, the Cardinals trailed early as Panthers kicker John Kasay kicked a 33-yard field goal for the only score of the period.

Hoping to rebound from their home loss to the Panthers, the Cardinals flew to FedExField for a Week 7 duel with former division rival Washington Redskins.

The Cards would recover their onside kick and got into position to attempt a game-winning 55-yard field goal from kicker Neil Rackers.

In the second quarter, Arizona continued to struggle as Tampa Bay kicker Matt Bryant nailed a 32-yard field goal for the only score of the period.

Late in the game, during the Cards last offensive drive, QB Kurt Warner would get intercepted by Safety Jermaine Phillips.

Coming off their home win over the Lions, the Cardinals flew to Paul Brown Stadium for a Week 11 interconference duel with the Cincinnati Bengals.

In the first quarter, the Cards trailed early as Bengals QB Carson Palmer completing a 19-yard TD pass to WR T.J. Houshmandzadeh.

The Bengals tried to come back as Palmer completed a 37-yard to WR Chris Henry, while RB DeDe Dorsey returning a blocked punt 19 yards for a touchdown.

Coming off an impressive road win over the Bengals, the Cardinals went home for a Week 12 NFC West rematch with the San Francisco 49ers.

In the first quarter, the Cards took flight early as QB Kurt Warner completed a 28-yard touchdown reception to WR Larry Fitzgerald.

In the fourth quarter, the Cardinals regained the lead with QB Tim Rattay completing a 2-yard TD pass to rookie TE Ben Patrick.

In the first quarter, Arizona jumped out to an early lead as CB Roderick Hood returned an interception 71 yards for a touchdown, along with QB Kurt Warner's 5-yard TD pass to TE Leonard Pope.

In the second quarter, Cleveland drew close as QB Derek Anderson completed a 6-yard TD pass to RB Jamal Lewis for the only score of the period.

Coming off their home win over the Browns, the Cardinals flew to Qwest Field for a Week 14 NFC West rematch with the Seattle Seahawks.

In the first quarter, Arizona trailed early as Seahawks kicker Josh Brown managed to get a 23-yard field goal, along with QB Matt Hasselbeck completing a 7-yard TD pass to WR Nate Burleson.

The Cardinals would get on the board as QB Kurt Warner completed a 5-yard TD pass to WR Bryant Johnson, yet Seattle increased their lead prior to halftime with Brown kicking a 41-yard field goal.

However, in the fourth quarter, the Seahawks pulled away as Hasselbeck completed a 3-yard TD pass to TE Marcus Pollard, RB Josh Scobey tackling Cardinals punter Mitch Berger in the end zone for a safety, and CB Marcus Trufant returning an interception 84 yards for a touchdown (with a failed PAT).

Hoping to recover from their divisional road loss to the Seahawks, the Cardinals flew to the Louisiana Superdome for a Week 15 intraconference duel with the New Orleans Saints.

The Cardinals were officially eliminated from playoff contention the next day, after the Minnesota Vikings defeated the Chicago Bears, meaning again that the home team hosting the Super Bowl would not be participating therein.