2007 is also noted for being defensive lineman Bryant Young's final season; the future Hall of Fame enshrinee was the last remaining member of San Francisco's Super Bowl XXIX championship team.

The team also addressed its wide-receiver needs by signing former Denver Bronco and Atlanta Falcon, Ashley Lelie and Seattle Seahawk, Darrell Jackson.

On the second day of the NFL Draft, the San Francisco 49ers traded a 4th round pick for Seattle Seahawks leading receiver, Darrell Jackson.

Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve at Bill Walsh Field at Monster Park, San Francisco, California Dressed up in their throwback uniforms, the 49ers began their 2007 campaign against their NFC West rival, the Arizona Cardinals in the second game of the Monday Night Football doubleheader.

However, in the second quarter, the Cardinals took the lead with kicker with Neil Rackers getting a 35-yard field goal and RB Edgerrin James getting a 7-yard TD run.

In the fourth quarter, Arizona jumped ahead with QB Matt Leinart completing a 5-yard TD pass to WR Anquan Boldin.

In the first quarter, the Niners trailed early as Rams QB Marc Bulger completed a 12-yard TD pass to WR Torry Holt for the only score of the period.

In the second quarter, Pittsburgh increased its lead with QB Ben Roethlisberger completing a 9-yard TD pass to TE Jerame Tuman for the only score of the period.

In the fourth quarter, Pittsburgh took control with Reed getting a 49-yard and a 35-yard field goal, while CB Bryant McFadden returned an interception 50 yards for a touchdown.

Afterwards, Seattle began to pound away with QB Matt Hasselbeck completing a 17-yard TD pass to WR Bobby Engram, along with Brown kicking a 31-yard field goal.

at Bill Walsh Field at Monster Park, San Francisco, California Trying to break a two-game skid, the 49ers stayed at home for a Week 5 interconference matchup with the Baltimore Ravens.

With QB Alex Smith out with a shoulder injury, back-up Trent Dilfer was given the start against the team to which he helped deliver a Super Bowl title.

With two minutes left in the fourth quarter, the 49ers had a chance to take the lead, but kicker Joe Nedney missed a 52-yard field goal and the Ravens ran out the clock.

In the first quarter, the Niners trailed early as Giants QB Eli Manning hooked up with WR Amani Toomer on a 4-yard TD pass (with a missed PAT) for the only score of the period.

In the third quarter, things got worse for the Niners as Giants DE Osi Umenyiora sacked Dilfer, causing a fumble, picked up the loose ball, and ran 75 yards for a touchdown.

at Bill Walsh Field at Monster Park, San Francisco, California Trying to snap a four-game skid, the 49ers went home for a Week 8 intraconference duel with the New Orleans Saints.

In the first quarter, San Francisco trailed early as Saints QB Drew Brees completed a 17-yard TD pass to WR Marques Colston, while kicker Olindo Mare nailed a 26-yard field goal.

In the first quarter, the Niners trailed early as Seahawks QB Matt Hasselbeck completed a 1-yard TD pass to TE Will Heller, along with kicker Josh Brown.

In the second quarter, San Francisco's struggles continued as RB Maurice Morris gave Seattle a 6-yard TD run for the only score of the period.

at Bill Walsh Field at Monster Park, San Francisco Trying to break their seven-game losing skid, the 49ers went home, donned their throwback uniforms, and played their Week 11 NFC West rematch with the St. Louis Rams.

In the first quarter, the Niners' struggles continued as Rams QB Marc Bulger completed a 3-yard touchdown reception to WR Torry Holt.

In the second quarter, San Francisco continued to struggle as Carolina QB Vinny Testaverde completed a 5-yard to TE Dante Rosario, along with CB Richard Marshall returning an interception 67 yards for a touchdown.

In the first quarter, the Niners trailed early as Vikings DT Kevin Williams returned an interception 18 yards for a touchdown, while kicker Ryan Longwell managed to get a 48-yard field goal.

at Bill Walsh Field at Monster Park, San Francisco Trying to snap a two-game skid, the 49ers stayed at home for a Saturday night interconference battle with the Cincinnati Bengals.

However, the Bengals took the lead as kicker Shayne Graham made a 24-yard field goal, while QB Carson Palmer completed a 52-yard TD pass to WR Chris Henry.

Rolling with the momentum from the previous week's upset, the 49ers took on the playoff-bound Buccaneers as their final home game of the season, and of perennial pro-bowler Bryant Young's career.

With the Buccaneers clinching their division in Week 15, and no improvement in their seed in sight, they treated it as a glorified exhibition game by resting the majority of their starters after the first few drives.

Although it wasn't an important game in the standings for either team, the 49ers had their pride – and maybe their head coach Mike Nolan's job – on the line, and the Bucs wanted to make sure that their momentum and edge kept up as they entered the playoffs.

The game came down to a matter of inches, as the Buccaneers final touchdown with 80 seconds remaining led to a failed 2-point attempt at a tying score; receiver Michael Clayton caught the pass in the back of the end zone but half of his foot came down out of bounds.