Long-time Palermo players Fábio Simplício and Mark Bresciano left the rosanero by 30 June after failing to agree for a contract extension with the club.

[2] The first high-profile move from Palermo was completed on 11 June, when the club announced the signing of Chilean prolific striker Mauricio Pinilla from Grosseto.

[10] As a replacement for Kjær, Palermo then chose to acquire young Argentine centre back Ezequiel Muñoz; the player was successively announced to have joined the club's Austrian training camp on 30 July, after he underwent a medical in Sicily.

[18] The first league game, played on 29 August, ended in a 0–0 home draw to Cagliari; on the very next day, Palermo announced the signing of Brazilian 18-year-old attacking midfielder João Pedro from Atlético Mineiro.

[23] Such result led to immediate rumours regarding an imminent dismissal of head coach Delio Rossi, that was informally confirmed by Zamparini himself in several interview throughout the day.

[25][26] After two more losses (against Lazio and Genoa, respectively), Cosmi achieved his first win in charge of Palermo by surprisingly defeating league-toppers AC Milan in a 1–0 home triumph, with Romanian defender Dorin Goian scoring the only goal of the game.

The final, that saw a massive participation from Palermo fans, ended however in a rather controversial 1–3 loss to Inter, with Muñoz scoring the only goal for the rosanero in a game the Sicilians were forced to play without key elements as Bačinović and Bovo, and with Goian getting injured in the first half to be replaced by Moris Carrozzieri, who was at his second game in the season after a two-year suspension due to cocaine usage.