The 2010 Shanghai Rolex Masters was a men's tennis tournament played on outdoor hard courts.

It took place at Qizhong Forest Sports City Arena in Shanghai, China.

Fourth-seeded Andy Murray won the singles title.

The following players received wildcards into the singles main draw:[2] The following players received entry from the qualifying draw:[3] The following players received entry as a Lucky loser into the singles main draw: Andy Murray defeated Roger Federer, 6–3, 6–2.

[4] Jürgen Melzer / Leander Paes defeated Mariusz Fyrstenberg / Marcin Matkowski, 7–5, 4–6, [10–5].