The 2018–19 Iowa State Cyclones men's basketball team represented Iowa State University during the 2018–19 NCAA Division I men's basketball season.

The Cyclones were coached by Steve Prohm, who was in his fourth season at Iowa State.

They played their home games at Hilton Coliseum in Ames, Iowa as members of the Big 12 Conference.

They lost in the first round of the Big 12 tournament to Texas.

*AP does not release post-NCAA tournament rankings.