The tournament was contested by 36 teams, beginning on 13 February and ending on 6 November, with Independiente Medellín winning their second title by defeating Deportivo Cali in the finals by a 4–3 aggregate score and qualifying for the 2020 Copa Libertadores.
Atlético Nacional were the defending champions, but were knocked out of the competition by Deportes Tolima in the quarterfinals.
This year the competition featured the return of the group stage, after being played under a single-elimination format in its entirety in the previous edition.
The seven group winners plus the best second-placed team qualified for the round of 16, where they were joined by the eight teams that qualified for CONMEBOL competitions for the 2019 season: Deportes Tolima, Junior, Independiente Medellín, Atlético Nacional, Once Caldas, La Equidad, Rionegro Águilas and Deportivo Cali.
Starting from this point, the cup continued as a single-elimination tournament, with all subsequent rounds being played as double-legged series.