The 2020–21 Botola Pro, also known as Botola Pro Inwi for sponsorship reasons, is the 64th season of the Premier League and the 10th under its new format of Moroccan Pro League, the top Moroccan professional league for association football clubs, since its establishment in 1956.
Chabab Mohammédia and Maghreb de Fès entered as the two promoted teams from the 2019–20 Botola 2.
Wydad AC are crowned champions of this edition three rounds before the end of the tournament with a record of 21 Botola.
The table lists the positions of teams after each week of matches.
The UMFP (Union Marocaine des Footballeurs Professionnels), in partnership with the Royal Moroccan Football Federation, organized the Night of Stars Award in its 7th edition, which celebrated the brilliants of the Botola Pro for the 2020/21 season.