The 2020–21 South African Premiership season (known as the DSTV Premiership for sponsorship reasons) was the 25th season of the Premiership since its establishment in 1996.
Mamelodi Sundowns won the title for the fourth consecutive year, qualifying for the 2021–22 CAF Champions League along with second placed AmaZulu.
Third placed Orlando Pirates and Nedbank Cup winners Tshakhuma Tsha Madzivhandila qualified for the 2021–22 CAF Confederation Cup.
The following teams have changed division since the 2019–20 season.
Relegated from 2019–20 South African Premier Division Promoted to 2020–21 South African Premiership [3]