The 2021–22 Gibraltar Women's Football League is the sixth season of 11-a-side women's football in Gibraltar since the territory joined UEFA in 2013, and FIFA in 2016.

Lions Gibraltar were the reigning champions from the previous season, which had been shortened due to the COVID-19 pandemic.

Note: Flags indicate national team as has been defined under FIFA eligibility rules.

Note: Gibraltar Wave were awarded a 3–0 walkover win over Lynx on 12 January after Lynx failed to field a team, as were Europa on 9 February.

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