The 2021 Holland Ladies Tour, also known as the 2021 Simac Ladies Tour is a road cycling stage race that took place in the Netherlands between 24 and 29 August 2021.

It was the 23rd edition of the Holland Ladies Tour, and part of the 2021 UCI Women's World Tour.

[1][2] All nine UCI Women's WorldTeams and seven UCI Women's Continental Teams made up the sixteen teams that participated the race.

[3][4] UCI Women's WorldTeams UCI Women's Continental Teams