The 2022 Open 13 Provence was a men's tennis tournament played on indoor hard courts.

It was the 30th edition of the Open 13, and part of the ATP Tour 250 series of the 2022 ATP Tour.

It took place at the Palais des Sports de Marseille in Marseille, France, from 14 through 20 February 2022.

[1] *per team The following players received wildcards into the main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: The following pairs received wildcards into the doubles main draw: The following pair received entry as alternates: