The 2022 Lamar Hunt U.S. Open Cup tournament proper featured both professional and amateur teams from the United States.
Qualification for the 2022 tournament included local qualifying matches contested by 90 amateur teams scheduled in 2021.
[1] Clubs playing in fully professional leagues may enter the tournament proper and bypass the qualification process.
[2] U.S.-based teams in Division I, II and III professional leagues qualify for the U.S. Open Cup automatically, provided they are eligible.
To be eligible, these teams must be members in good standing of their leagues on December 31, 2021, and remain so through the 2022 U.S. Open Cup Final.
[3] The cup winner enters the tournament proper in the first round with the other Open Division clubs.
Byes are distributed randomly and are meant to avoid unnecessary travel but are kept to a minimum to preserve the integrity of the qualification tournament.
[3] The eleven winners of the fourth round of local qualifying will join them as the twelve Open Division teams in the tournament proper.
[2] Four rounds of local qualifying matches resulted in 11 clubs advancing to the tournament proper.