Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.

This gene encodes a ribosomal protein that is a component of the 60S subunit.

The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug.

Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development.

This gene used to be referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a).