[7][8] Animal mitoribosomes only have two rRNAs, 12S (SSU) and 16S (LSU), both highly minimized compared to their larger homologues.
[9] A variety of methods have evolved to fill in the gap left by a missing 5S, with animals co-opting a Mt-tRNA (Val in vertebrates).
[1] As mitochondria evolved however, the mitoribosome has significantly diverged from its bacterial cousins leading to differences in configuration and function.
[13] Examples of diseases in humans caused by these mutations include Leigh syndrome, deafness, neurological disorders, and various cardiomyopathies.
[13] In plants, mutation in mitoribosomal proteins can result in stunted size and distorted leaf growth.