The A27 motorway is a branch of the A2 Egnatia Odos motorway at Kozani, which leads towards Ptolemaida and from there to Florina and the Niki border crossing with North Macedonia.

Within 2012 tenders were announced for the construction of the 14,5 km section from Florina up to the border crossing with North Macedonia as a motorway.

[1] Construction started in 2013 and finished in December 2015.

The northern part from Florina to Niki was opened to traffic on 20 May 2016.

The section from Ptolemaida to Florina is operational as an expressway (GR-3) and is planned to be upgraded to a motorway sometime until 2025.