466100040260ENSG00000123268ENSMUSG00000080968P18846n/aNM_005171XM_036162179NP_005162n/aCyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene.

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family.

It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities.

[5] Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma.

[5][6] ATF1 has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.