Anisodamine, also known as 7β-hydroxyhyoscyamine, is a mAChR anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China.

[1] It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt of the natural enantiometer.

[3] Anisodamine is a naturally occurring tropane alkaloid found in some plants of the family Solanaceae including Datura.

It poorly passes the blood-brain barrier and binds brain mAChR less tightly.

In rodents, it exhibits weaker CNS effects,[6] causes less mydriasis, but has approximately equal or slightly lower potency in blocking spasms and in reducing GI motility.