In 1909, the Greek Orthodox community paid $18,000 for the lot of city land on which the cathedral stands today.

It was built after an Athenian cathedral and is currently the oldest surviving Chicago building in the style of a Byzantine church.

The burden of the Great Depression prompted the Greek Orthodox community to rally together and save the churches from financial ruin through various fundraising activities.

Also in this era, the entire building was raised from its foundation and moved back to accommodate for the widening of LaSalle Street.

This article on an Eastern Orthodox church building in the United States is a stub.