[1] Antiparastics may be given via a variety of routes depending on the specific medication, including oral, topical, and intravenous.
The Egg hatch assay can be used to determine whether a parasite causing an infection has become resistant to standard drug treatments.
[10] Early antiparasitics were ineffective, frequently toxic to patients, and difficult to administer due to the difficulty in distinguishing between the host and the parasite.
[4] Between 1975 and 1999 only 13 of 1,300 new drugs were antiparasitics, which raised concerns that insufficient incentives existed to drive development of new treatments for diseases that disproportionately target low-income countries.
This led to new public sector and public-private partnerships (PPPs), including investment by the Bill and Melinda Gates Foundation.