One segment of 27.22 miles (43.81 km) runs from US 412B in Walnut Ridge east to Highway 135 in Oak Grove Heights.

Both routes are maintained by the Arkansas State Highway and Transportation Department (AHTD).

The route meets Highway 90 in O'Kean, and runs concurrently with it northeast to Delaplaine.

The route continues east to Oak Grove Heights, where it terminates at Highway 135.

The route begins at Highway 135 in Lafe and runs east to Marmaduke, where it crosses US 49.