Arquata Scrivia (local dialect: Auquâ) is a comune (municipality) in the Province of Alessandria in the Italian region Piedmont, located about 100 kilometres (62 mi) southeast of Turin and about 35 kilometres (22 mi) southeast of Alessandria.

The name derives from the Latin arcuata (arched), due to the presence of an aqueduct supplying the nearby Roman town of Libarna, on the Via Postumia.

It is mentioned as a castrum (fortress) in the 11th century, and later was contended between the Republic of Genoa and the commune of Tortona: after they signed a peace agreement in 1227, they dismantled the castle.

In 1313, it was given by emperor Henry VII to the Genoese Spinola family, who were named marquisses of the town in 1641.

A team of Red Cross nurses headed by Mrs. Marie Watkins used the theatre at Arquata Scrivia as a recreation room and canteen for British soldiers.