[5] Side effects may include sleepiness, vision changes, dry mouth, rapid heart rate, triggering of glaucoma, and severe allergies.

[20] Hyoscine butylbromide is effective in reducing the duration of the first stage of labour, and it is not associated with any obvious adverse outcomes in mother or neonate.

[21] It is also used during abdominal, pelvic MRI, virtual colonoscopy, and double barium contrasted studies to improve the quality of pictures.

[13] Hyoscine butylbromide is still capable of affecting the chemoreceptor trigger zone, due to the lack of a well-developed blood-brain barrier in the medulla oblongata, which increases the antiemetic effect it produces via local action on the smooth muscle of the gastrointestinal tract.

Cautions should be taken for those with untreated glaucoma, heart failure, benign prostatic hyperplasia with urinary retention as hyoscine may exacerbate these conditions.

[23] Hyoscine butylbromide reduces smooth muscle contraction and the production of respiratory secretions.