[5][6] Chemokine receptor-like 1 is a G protein-coupled receptor for the chemoattractant adipokine chemerin[7] and the omega-3 fatty acid eicosapentaenoic acid-derived specialized pro-resolving molecule, resolvin E1 (see Specialized proresolving mediators#EPA-derived resolvins (i.e.
CMKLR1 expression by plasmacytoid dendritic cells and macrophages also helped foster this idea.
In vitro chemotaxis assays showed it to be utilized in attracting these cells.
[13] The same model showed that this particular molecule enhances macrophage efferocytosis (phagocyting apoptotic cells).
[20] This article incorporates text from the United States National Library of Medicine, which is in the public domain.