XCL1

These both are called Lymphotactin, alpha and beta form, and claim special characteristics only found between the two.

[12] In humans, XCL1 is closely related to another chemokine called XCL2, whose gene is found at the same locus on chromosome 1.

[11] Both of these chemokines share many genetic and functional similarities; however XCL2 has only been known to be observed in humans and not in mice.

[14] XCL1's gene is found on the long arm of chromosome 1, located on cytogenetic band q24.2 as seen in the infobox.

[8] This gene encodes for the 114-amino acid protein called XCL1 which is similar to other chemokines except that it lacks the first and third cysteine characteristics.

[8] Gene mapping of this chemokine family shows similarities in their intron and exon locations with only one distinct difference.

[5] This simple difference in disulfide bonds changes the overall tertiary structure of XCL1 from other chemokines.

[7] The pair of XCL1 and XCR1 are known to be involved in cross-presentation, antigen uptake, and induction of innate as well as adaptive cytotoxic immunity.