CXCL13

4ZAI, 5CBA, 5CBE1056355985ENSG00000156234ENSMUSG00000023078O43927O55038NM_006419NM_001371558NM_018866NP_006410NP_001358487NP_061354Chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a protein ligand that in humans is encoded by the CXCL13 gene.

As its other names suggest, this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5.

[5][7] CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues[8] and is expressed highly in the liver, spleen, lymph nodes, and gut of humans.

[5] The gene for CXCL13 is located on human chromosome 4 in a cluster of other CXC chemokines.

This article on a gene on human chromosome 4 is a stub.