[2] The domain is about 100 amino acids in length and is composed of four alpha helices.

[4] The CH domain is involved in actin binding in some members of the family.

However, in calponins there is evidence that the CH domain is not involved in its actin binding activity.

The structure of an example CH domain has been determined using X-ray crystallography.

[6] Human genes encoding calponin homology domain-containing proteins include: