Camphorsultam, also known as bornanesultam, is a crystalline solid primarily used as a chiral auxiliary in the synthesis of other chemicals with a specific desired stereoselectivity.

This reaction was originally performed as a catalytic hydrogenation using Raney Nickel,[2] but the modern preparation instead uses lithium aluminium hydride for the reduction.

[4][5] Due to its ability to form derivatives through its nitrogen atom and the structural rigidity of its chirality, camphorsultam is often used in reactions as a chiral auxiliary in order to allow a reaction to proceed with very specific stereoselectivity.

During the synthesis of Manzacidin B, camphorsultam is used in order to obtain the desired stereoselective product.

Stereoselectivity can be further increased if substrates are equipped with two chiral auxiliaries, acting in a cooperative fashion.