[3] Ho is a Vietnamese-Chinese American and was born in Los Angeles, California, but grew up in the San Francisco Bay Area.

[9] Ho started posting fitness videos on YouTube in 2009 after she decided to move from Los Angeles, California to Boston, Massachusetts for a full-time job as a fashion buyer.

[14][4] She had been a part-time Pilates instructor and wanted to provide the students she was leaving with online fitness workouts after she moved to Boston.

[14] She found teaching Pilates this often physically tiring, but because she was not working full-time, she had time to make more workout videos.

[30] In an interview with EContent Magazine, Ho stated that she believes that one reason for her success on YouTube is because she keeps her videos "fun and playful.

"[17] She was interviewed by Forbes in 2012 as a woman who is rapidly becoming a star on YouTube along with several other women such as Issa Rae and Cassandra Bankson.

"[21] Sharecare also ranked her as the number 2 online influencer making a difference in the world of fitness just behind Jillian Michaels.

[2][12] In January 2014, MarketWatch[32] reported that Ho was first on their top 10 list of Social HealthMarkers on fitness by Sharecare.

[36][37] According to Ro Kalonaros, writing for Shape, "The line is a mix between high fashion and practical—think peplum and bold prints.

[39][8] A YOLO meal consists of what is considered traditionally unhealthy food such as pizza, french fries, and ice cream.

[39] Kit Steinkellner reported in the Huffington Post that when she followed this approach she found that it increased her desire for both YOLO meals and healthy food.

[40] When she first began to upload videos to YouTube and answering questions about fitness on her blog, she thought of herself only as only an instructor.

[20] She now views her role as extending beyond a fitness instructor to include helping people get healthier and feeling better about their bodies.

[20][8] In January 2016, Ho came out to say that she struggled with an eating disorder following the extreme training and calorie restriction she did in preparation for a bikini competition in 2012.

[45] She said she was working out up to four hours a day while maintaining a 1,000 calorie diet in the lead up to the fitness and figure competition, and that her mind felt cloudy during this period.

In April 2015, Ho responded to an increasing number negative comments about her body by creating a video that quickly went viral.

"[50] On August 22, 2017, Ho announced her engagement to longtime boyfriend Sam Livits on her official Instagram page.