The cellular apoptosis susceptibility protein (CAS) is an exportin which in the nucleus is bound to RanGTP.
[1] Apoptosis is a specialized sequence of events that a cell can induce for programmed death.
Along with this correlation, in the absence of the CAS protein in a cell, there is an inhibition of apoptosis Along with being an inducer of apoptosis, CAS also plays a role in being a checkpoint for cell cycle.
The Cas family of proteins can be divided into 4 functional domains: expression, interference, adaption, and ancillary.
Lastly, the ancillary domain helps with regulation of the gene and other CRISPR functions.