Chamazulene

Chamazulene is an aromatic chemical compound with the molecular formula C14H16 found in a variety of plants including in chamomile (Matricaria chamomilla), wormwood (Artemisia absinthium), and yarrow (Achillea millefolium).

[1] It is a blue-violet derivative of azulene which is biosynthesized from the sesquiterpene matricin.

[2] Chamazulene has anti-inflammatory properties in vivo and inhibits the CYP1A2 enzyme.

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Biosynthesis of chamazulene ( 3 ) from matricin ( 1 ) via a carboxylic acid of chamazulene ( 2 ).