[1] The hospital is also known for its first building which was constructed in 1909 in Baroque architecture with stucco, and currently houses the "Thai Traditional Medicine Museum".

It is also a leading traditional Thai medicine hospital and plans to develop into a major hub in ASEAN.

[2] In 1909, Chao Phraya Abhaibhubejhr (Choom Abhaiwongse), royal commissioner of Monthon Burapha and the Governor of Phra Tabong Province, ordered the construction of the building by the French architectural company, Howard Erskine, to resemble the governor's residence in Battambang.

The purpose was to serve as a royal residence for King Chulalongkorn in the event he visited Prachinburi Province.

[3] In 1990, the Chao Phraya Abhaibhubejhr Building was registered as an ancient monument by the Fine Arts Department of the Ministry of Culture.