It is classified by the Ministry of Public Health as a regional hospital.

It has a Collaborative Project to Increase Production of Rural Doctors (CPIRD) Medical Education Center which trains doctors for the MOPH-Mahidol CPIRD Program.

[1] The foundation stone for Ratchaburi Hospital was laid on 2 April 1941 and the hospital opened in 1941, consisting of a small patient building, doctor's lodgings, and a kitchen.

Initially, the hospital had a capacity of 25 beds.

On 30 September 2003, the hospital received ISO 9002:20031 accreditation and in 2006 received HA (Hospital Accreditation).