The station is located at a crossing of five railway lines:[3] The railway station was built in Neorenaissance style in 1865 and was designed by Viennese architect Heinrich von Hügel.

In 1872 the private company Emperor Franz Joseph Railway (German: k.k.

After the fall of the Austro-Hungarian Empire and declaration of independent Czechoslovakia the station was renamed to Cheb, but because of the huge German-speaking population in the city all station signs were bilingual.

During the Second World War, on 8 April 1945, the United States air forces conducted a raid on the town and most of the station area, except the main building, was destroyed (Kunst 1992).

[clarification needed] The design, which was prepared in 1956-59 by the architect Josef Danda (who also designed Pardubice station) in Brussels style, was declared by the Czech Ministry of Culture as a cultural monument.