Coclaurine

Coclaurine is a nicotinic acetylcholine receptor antagonist[1] which has been isolated from a variety of plant sources including Nelumbo nucifera, Sarcopetalum harveyanum,[2] Ocotea duckei,[3] and others.

It belongs to the class of tetrahydroisoquinoline alkaloids.

Dimerization of coclaurine leads to the biscoclaurine alkaloids such as cepharanthine.

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