Corrole

Corroles can be prepared by a two-step process, beginning with the condensation reaction of a benzaldehyde with pyrrole.

The open-ring product, a bilane (or tetrapyrrane), is cyclized by oxidation, typically with p-chloranil:[1] Corrole and porphyrins differ in several ways.

See "Porphyrins and similar compounds" in conjugated systems for more about these side by side images of porphyrin, chlorin, and corrin structures: Corroles have been attached to a wide range of transition metals,[1][3] main group elements,[4] and lanthanides,[5] actinides.

[7] Additionally, corroles and their metal complexes have been demonstrated to be useful as imaging agents in tumor detection,[8] oxygen sensing,[9] for prevention of heart disease,[10] in synthetic chemistry as oxo, imido, and nitrido transfer agents,[11] and as catalysts for the catalytic reduction of oxygen to water,[12] and hydrogen production form water under aerobic conditions.

Protein-corrole particles have been investigated as carriers of theranostic cargo for tumor targeting.