Del Parque operated for over 27 years until it was closed due to the high pedestrian traffic in the area where the station was located.

After several attempts, the train finally made its inaugural trip on 29 August 1857 from the Parque station, carrying notable people of the time such as Valentín Alsina, Bartolomé Mitre, Domingo Sarmiento and Dalmacio Vélez Sársfield.

After a brief stop at San José de Flores, the train arrived at Floresta, the terminal station of the line.

In 1873 the Government considered moving the terminus to Once (the first stop after Del Parque) due to the growing population in the area between both stations.

In April 1878 the Municipality of Buenos Aires promulgated by decree the moving of the station to Once, also closing the Once–Del Parque section, though it did not take effect until 1883.