The College of Computing & Informatics has faculty and administrative offices, research laboratories, collaborative learning spaces, and classrooms located at 3675 Market Street (University City Campus) Philadelphia, PA.

Details regarding the history of the iSchool is below: The College of Computing & Informatics offers six undergraduate programs: the Bachelor of Science in Information Systems (BSIS), Data Science (BSDS), Information Technology (BSIT), Software Engineering (BSSE), Computing and Security Technology, Computer Science (CS), and the BS/MS Accelerated Degree Program which allows students to complete both a bachelor's degree and a master's degree in five years.

Most of the undergraduates take advantage of Drexel's long-standing co-op program to get real-world work experience before graduation.

[15] In 2019 the school was ranked in the top 20 in the US for Online Graduate Computer Information Technology Programs by U.S.News & World Report.

Constructed in 1904, the Hospital for the Treatment of Consumption and Related Diseases was named after Benjamin Rush, the famous 18th-century Philadelphia physician and one of the signers of the Declaration of Independence.

[19] In 1961, Drexel University acquired the building to in part house its Graduate School of Library Science.

In April 2019 the college consolidated facilities for faculty, staff, and students, moving into leased space in uCity Square, a complex of buildings in University City.

State of the art offices and classrooms dedicated to the College of Computing & Informatics occupied two floors of the building at 3675 Market Street.