8892217715ENSG00000119718ENSMUSG00000004788P49770Q99LD9NM_014239NM_145445NP_055054NP_663420Translation initiation factor eIF-2B subunit beta is a protein that in humans is encoded by the EIF2B2 gene.

[5][6] Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis.

It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits.

EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP.

This article on a gene on human chromosome 14 is a stub.