3D3M, 3L6A, 4IUL198213690ENSG00000110321ENSMUSG00000005610P78344Q62448NM_001418NM_001042559NM_001172705NM_001040131NM_013507NP_001036024NP_001166176NP_001409NP_001035221NP_038535Eukaryotic translation initiation factor 4 gamma 2 (also called p97, NAT1, and DAP-5) is a protein that in humans is encoded by the EIF4G2 gene.

[5][6] Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G.

The protein encoded by the eIF4G2 gene shares similarity with the C-terminal region of eIF4G1 that contains the binding sites for eIF4A and eIF3.

In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon.

Alternatively spliced transcript variants encoding different isoforms of this gene have been described.