EnCor Biotechnology

[1] In late 2001 EnCor rented lab space at the Sid Martin Biotechnology Incubator, a facility dedicated to commercialization of intellectual property generated in the University of Florida.

Following this move the EnCor laboratory produced an increasing number of novel antibodies which were made, characterized, documented, manufactured and subjected to rigorous quality control.

[2] EnCor has always collaborated with basic scientists and clinicians to produce articles in peer-reviewed scientific publications focused on the examination of various plasma, serum and CSF biomarkers of nervous system damage and degeneration.

In 2022 EnCor, in collaboration with researchers at the University of Florida described a novel class of antibodies to neurofilament light chain with the HGNC name NEFL, although the protein is usually referred to as NF-L.

EnCor is well known for the quality of its cell, tissue and western blotting images, many of which have been made available on Wikipedia Commons and widely used in books, articles, posters, for teaching, advertising and many other purposes, see [1].

Rat brain cells grown in tissue culture and stained, in green, with an EnCor mouse monoclonal antibody to neurofilament subunit NF-L, ( HGNC name NEFL ), which reveals a large neuron. The cells in the above image were also stained in red with an EnCor rabbit antibody to α-internexin , which in this culture is found in neuronal stem cells.
A formalin fixed and paraffin embedded section of human cerebellum stained with an EnCor mouse monoclonal antibody to NF-L revealed with a brown dye, cell nuclei are revealed with a blue dye. Nuclear rich region at left is the cerebellar granular layer, the region at the right with fewer nuclei is the cerebellar molecular layer. The NF-L antibody binds processes of basket cells, parallel fiber axons, the perikarya of Purkinje and some smaller neurons and various other fine axons.