Ethyl caffeate

Ethyl caffeate is an ester of a hydroxycinnamic acid, a naturally occurring organic compound.

[3] Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro or in mouse skin.

It can be considered as a promising natural compound for future application in chronic liver disease.

[3] Pharmacophore modeling, molecular docking, and molecular dynamics simulation studies also indicate that ethyl caffeate is a potential inhibitor of the aldosterone synthase (CYP11B2), a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure.

[4] Ethyl caffeate reacts with methylamine to produce green pigments.

UV spectrum of ethyl caffeate.