Ferrandina (Lucano: Frannine) is a town and comune in the province of Matera, in the Southern Italian region of Basilicata.

Towns close are: Pomarico, Miglionico, Salandra, Pisticci, Grottole, San Mauro Forte and Craco.

Right after, the Dominicans created an agricultural center specialized in the production of wool, highly valued in the Kingdom of Naples.

In March 1862, brigand leader Carmine Crocco confronted and destroyed here a company of Italian troops.

In 2003 Ferrandina took part in protest against the decision to build a nuclear waste center despite no evidence that it would negatively effect the community.