Fibrillin is a glycoprotein, which is essential for the formation of elastic fibers found in connective tissue.

[2] Fibrillin is secreted into the extracellular matrix by fibroblasts and becomes incorporated into the insoluble microfibrils, which appear to provide a scaffold for deposition of elastin.

[3] Marfan syndrome is a genetic disorder of the connective tissue caused by defected FBN1 gene.

Instead, short fragments have been produced recombinantly and their structures solved by X-ray crystallography or using NMR spectroscopy.

[1] The microfibrils that are made up of fibrillin protein are responsible for different cell-matrix interactions in the human body.