The book was part of a line of three superhero comics based on the Universal Monsters characters; the other two were Dracula and Werewolf.
Created in 1866 by a reclusive scientist referred to only as "the Doctor" who endowed him with a superior intellect and the strength of fifty men, Frankenstein lay dormant for over a hundred years under the ruins of an abandoned castle near the large modern American metropolis of Metropole City.
Upon awakening thanks to a convenient lightning bolt, he dons a lifelike rubber mask to hide the fact that his white-haired and black-browed head has pale green skin (the rest of his tall, muscular body has a Caucasian flesh tone) and takes the name "Frank Stone", a pseudonym inspired by a fallen chunk of masonry with the word "FRANK" engraved in it.
[3] Befriending elderly millionaire philanthropist Henry Knickerbocker after rescuing him from a traffic accident (and who, by an amazing coincidence, is the son of a man who had been his long-dead creator's friend and business partner), when the old man dies from a heart attack he leaves his "nephew" Frank his vast fortune, allowing him the financial freedom to devotes his life to being a scarlet-suited superhero.
His archenemy is the amazingly "Mini-Me"-like midget mad scientist Mr. Freek who likes to ride around on the shoulders of his huge and extremely powerful pet gorilla Bruto.