The player controls Frankenstein's monster as he stomps through the streets of Ingolstadt, Bavaria, in the year 1793 seeking revenge against a certain man named Victor for rejecting him once he was created.

The common folks that strive to kill Frankenstein's monster are highly ignorant about modern science and believe that he is truly a demon.

The game follows the plot of the movie closely with some alterations or padding, most notably the removal of Elizabeth's death scene yet her resurrection as an abomination is kept and she is fought as a boss that dies after being accidentally set on fire.

Frankenstein also has an additional attack; a blue ball of negative energy that pops up when the player releases the button.

About the only interesting thing Sony did with Mary Shelley's Frankenstein was to cast it as a role-playing, rather than an action, game, but it's still awful: Even fans of the Kenneth Branagh movie will find it hard to get past the first scene, in which Frankenstein's monster hobbles around the doctor's lab like an aged pensioner looking for his Social Security check.