There have been many comic book adaptations of the monster story created by Mary Shelley in her 1818 novel Frankenstein; or, The Modern Prometheus.

[1] Considered by comics historians to be "America's first ongoing comic book series to fall squarely within the horror genre",[2][3] the feature, set in New York City circa 1930, starred a guttural, rampaging creature actually dubbed "Frankenstein" (unlike Shelley's nameless original monster).

In Prize Comics #11 (June 1941), Briefer dropped the "Frank N. Stein" pen name of the previous three stories and introduced the doctor's adopted son Denny "Bulldog" Dunsan as Frankenstein's ongoing antagonist.

Frost; the non-superpowered teens Yank and Doodle ("America's Fighting Twins"); and the namesake characters from the humor feature "General and the Corporal".

[4] As with many comics characters of the time, the monster found himself in the European theater of World War II fighting Nazis.

The character managed to break free of his conditioning and destroy the Germans' hypnosis machine, but then rampaged through Europe for a while with a female vampire, Zora, and a male zombie, Rollo.

[8] Like many returning veterans, Frankenstein settled into small-town life, becoming a genial neighbor who "began having delightful adventures with Dracula, the Wolfman and other horrific creatures.

[2] Briefer, with his trademark "loose and smooth ink and brush skills" began telling stories that would "straddle some amorphous line between pure children's humor and adventure and an adult sensibility about the world".