1MEJ, 1MEN, 1MEO, 1NJS, 1RBM, 1RBQ, 1RBY, 1RBZ, 1RC0, 1RC1, 1ZLX, 1ZLY, 2QK4, 2V9Y, 4EW1, 4EW2, 4EW3, 4ZZ2, 4ZZ3, 4ZZ1, 4ZYV, 4ZZ0, 4ZYY, 4ZYX, 4ZYZ, 4ZYT, 4ZYU, 4ZYW261814450ENSG00000262473ENSG00000159131ENSMUSG00000022962P22102Q64737NM_000819NM_001136005NM_001136006NM_175085NM_010256NM_001357351NP_000810NP_001129477NP_001129478NP_780294NP_034386NP_001344280Trifunctional purine biosynthetic protein adenosine-3 is an enzyme that in humans is encoded by the GART gene.

[5] This protein is a trifunctional polypeptide.

It has phosphoribosylamine—glycine ligase (EC 6.3.4.13), phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), AIR synthetase (FGAM cyclase) (EC 6.3.3.1) activity which is required for de novo purine biosynthesis.

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