It flows east for several tenths of a mile, entering Mahoning Township, Montour County and crossing a road.

It continues flowing southwest, on the northern side of Red Point Hill, before turning west-southwest and then south.

After several tenths of a mile, the stream crosses U.S. Route 11 and reaches its confluence with the Susquehanna River.

[4] A bridge carrying US Route 11 crosses Gaskins Run in Northumberland County, Pennsylvania.

[3] Gaskins Run was listed in the Geographic Names Information System on August 2, 1979.

[4] The bridge carrying US Route 11 over Gaskins Run was repaired after a flood in 1996 for a cost of $4,000.